The Imperial College Healthcare NHS Trust's Hepatology Clinical Research Facility (CRF) for clinical research and investigation is based on the 10th Floor of the Queen Elizabeth Queen Mother Wing at St Mary's Campus and provides a state of the art, designated area for hepatology academics and hepatology clinicians to perform clinical research projects involving both patients with liver conditions and healthy volunteers.

The postwill specifically help Principal Investigators and the research nursing team with patient recruitment into commercially sponsored clinical drug trials (alcohol, hepatitis, and fatty liver) and the ongoing management of patients according to the study protocols.

In undertaking this role, the Clinical Research Fellow will gain experience in the management of clinical trials and novel therapeutics in chronic liver disease.

The post is initially for 6 months, but will be renewable, and is suitable for a junior grade doctor (FY2 - FY5) who has a minimum of 1 year's post registration, recent experience of working in the NHS in a medical post, and who is looking to learn and develop clinical research skills. GMC registration and licence to practice are essential.

Main duties of the job

Support the timely delivery of clinical studies, in-line with the requirements of sponsors, GCP (Good Clinical Practice), and other appropriate guidelines and regulations

Provide medical assessment and cover for selected studies in the Hepatology CRF working alongside other clinical teams

Perform clinical procedures as appropriate to the assigned study (including, but not limited to, clinical examinations or testing, insertion of intravenous lines, assessment of adverse events and management of medical emergencies)

Ensure that patients/volunteers in assigned studies give fully informed consent in writing before commencing a study

Assess and interpret safety and clinical data from assigned studies, e.g. vital signs, ECG's, laboratory tests, adverse events etc.

Follow up and report Adverse Events as necessary. Communicate safety issues to the Principal Investigator, report Serious Adverse Events in accordance with Good Clinical Practice

Ensure that all clinical activities within the CRF are conducted in accordance with approved Standard Operating Procedures (SOPs)

Attend clinics and provide clinical cross cover where appropriate

Be responsible for specific study-related medical decisions as agreed with the Principal Investigators

Assess the eligibility of patient referrals for trials, and maintain and update a screening list

About us

At Imperial College Healthcare you can achieve extraordinary things with extraordinary people, working with leading clinicians pushing boundaries in patient care. Become part of a vibrant team living our values - expert, kind, collaborative and aspirational. You'll get an experience like no other and will fast forward your career. Benefits include career development, flexible working and wellbeing, staff recognition scheme. Make use of optional benefits including Cycle to work, car lease schemes, season ticket loan or membership options for onsite leisure facilities.

The statutory requirement to be fully Covid-19 vaccinated as a condition of employment from April 2022 is subject to legislative review. At Imperial College Healthcare NHS Trust, we strongly encourage and support vaccination uptake as this remains the best line of defence against COVID19. The successful applicant may have contact with patients and service users and as part of our pre-employment checks and risk assessments, we will ask all candidates to confirm whether or not they have been fully vaccinated or have a medical exemption.

As part of our continued response to Covid19 we are still conducting the majority of our interviews virtually.

We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part-time or job share. Please talk to us at interview.

Job description

Job responsibilities

The postholder will work closely with members of the Hepatology Research team to deliver expert clinical research. They will:

• Support the delivery of clinical studies, in-line with requirements of sponsors, GCP (Good Clinical Practice), and other appropriate regulations
• Provide medical assessment and cover for studies in the Hepatology CRF
• Perform clinical trial procedures (clinical examinations, insertion of intravenous lines, assessment of adverse events and management of medical emergencies, etc)
• Ensure patients give full informed consent before starting a study
• Assess and interpret safety and clinical trial data (vital signs, ECG's, laboratory tests, AEs etc).
• Follow up and report AEs. Communicate safety issues to the Principal Investigator, report SAEs in accordance with Good Clinical Practice
• Attend clinics and provide clinical cross cover where appropriate
• Be responsible for specific study-related medical decisions as agreed with the Principal Investigator
• Assess the eligibility of patients for trials, maintain and update screening lists
• Accept delegated responsibility to ensure that trials in the Hepatology CRF are carried out safely and in compliance with the protocol
• Evaluate and manage chronic adverse drug reactions and manage acute toxicological emergencies under the supervision of the consultants in charge
• Maintain accurate and accessible research records and medical notes
• Participate in research meetings, study review meetings and meetings with Principal Investigators and study sponsors
• Any other duties as may be deemed reasonable by senior clinical staff of the Hepatology CRF

Person Specification

Education/ qualifications

Essential

• MBBS or equivalent
• full valid GMC Registration with a licence to practise

Desirable

• Postgraduate specialist qualification e.g. MRCP or equivalent

Clinical skills

Essential

• Appropriate to job description

Relevant experience in specialty/Sub-specialty

Essential

• 1 year's post- registration recent experience in the NHS in a medical or surgical post
• Physical examination
• ECG, chest X ray, other radiology interpretation, biochemistry, haematology results interpretation
• Venipuncture, IV lines
• Ability to learn and implement new study related clinical skills

Desirable

• Hepatology clinical experience

Audit

Essential

• Knowledge of NHS processes and pressures
• Experience of teaching students and junior medical staff
• Understanding of principles of clinical audit

Desirable

• Clinical service development and research experience
• Previous experience of audit

Language

Essential

• Able to speak and write English to the appropriate standard necessary to fulfill the job requirements

Employer details

Employer name

Imperial College Healthcare NHS Trust

Address

St Mary's Hospital

London

W2 1NY

Any attachments will be accessible after you click to apply.

290-TDPA-195