Specialist Grade Doctor and Medical Lead in Haemopoietic Stem Cell Processing

The Clinical Haematology Department based at Hammersmith Hospital continues to expand and develop innovative treatment pathways to drive forward the high standards of care that we aspire to deliver for all our patients. This includes the John Goldman Centre for Cellular Therapy that provides highly specialist clinical, technical and scientific services for patients undergoing stem cell transplantation and immunotherapy. In addition to supporting the routine clinical stem cell transplant programme, the JGCCT also collaborates on the development and manufacture of new cellular therapies. The laboratory is located in a purpose built facility fully accredited by the HTA and JACIE. It additionally holds IMP and ATMP MHRA licenses.

Applications are invited from enthusiastic, well-motivated and organised individuals who would like to fill in this key post. The Specialist Grade Doctor will be the laboratory Medical lead in Clinical Trials service development such as validations, IMP introduction into the laboratory including both commercial and in-house developments. The post holder will expected to be involved in quality system development, training, data management and in new/on-going clinical trials research, bringing new therapies into clinical practice.

Main duties of the job

The Medical Lead: Haemopoietic Stem Cell Processing will:

Use and develop specialist skills within the Quality Testing Dept. in order that patient evaluation and product quality testing are carried out appropriately and in a timely manner conducive to good patient management.

Use and develop specialist skills within the Processing Dept. in the controlled working environment, clean rooms, and associated areas, to maintain regulatory compliance and a safe environment for the processing of cell harvests for clinical use.

Use and develop specialist skills to help translate discoveries made during research into clinical practice.

The post holder will be the lead in supporting Clinical Trials within the laboratory from a Site Initiation Visit by a Sponsor to an Investigational Product (IP) receipt, storage, processing, and infusion as directed by the Head of Operations and Regulatory Affairs and Clinical Trials Pharmacists.

In carrying out these duties, the post holder will maintain close communication with the Trial Sponsor, PI, QP, Clinical Trials Pharmacists, Medical, Nursing and Pharmacy staff attached to the Bone Marrow Transplant Unit activities and Clinical trials office based at Hammersmith Hospital, the Paediatric team based at St Mary's Hospital and any other relevant departments within Imperial College NHS Trust and outside the Trust.

About us

At Imperial College Healthcare you can achieve extraordinary things with extraordinary people, working with leading clinicians pushing boundaries in patient care. Become part of a vibrant team living our values - expert, kind, collaborative and aspirational. You'll get an experience like no other and will fast forward your career. Benefits include career development, flexible working and wellbeing, staff recognition scheme. Make use of optional benefits including Cycle to work, car lease schemes, season ticket loan or membership options for onsite leisure facilities.

The statutory requirement to be fully Covid-19 vaccinated as a condition of employment from April 2022 is subject to legislative review. At Imperial College Healthcare NHS Trust, we strongly encourage and support vaccination uptake as this remains the best line of defence against COVID19. The successful applicant may have contact with patients and service users and as part of our pre-employment checks and risk assessments, we will ask all candidates to confirm whether or not they have been fully vaccinated or have a medical exemption.

As part of our continued response to Covid19 we are still conducting the majority of our interviews virtually. We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part-time or job share. Please talk to us at interview.

Job description

Job responsibilities

Please refer to full job description and person specification provided.

The post holder will be actively involved in supporting the Research Biobank both in the receiving and processing of samples, maintenance, and support of Biobank cryo-storage facilities, requests for samples, sample distribution and data management.

They will be expected to provide on rotation with the other members of the team, an out of hours service. This will involve occasional weekend and evening work plus the provision of an off-site on-call

Person Specification

Education/Qualifications

Essential

• MBBS Degree
• Full GMC registration with a current licence to practise at time of appointment
• Professional training in haematology
• Good Manufacturing Practice (GMP) training

Experience

Essential

• Must have twelve (12) years minimum post graduate experience, at least four/six (4/6) of which must be in Haematology
• Minimum of 4/6 years' experience in Haematology
• Minimum of 4/6 years' experience in Cellular Therapy/ Immuno-phenotyping / Diagnostic Lab, Blood Transfusion Science, Immunology or ATMP development laboratory with GMP
• ATMP process development experience
• Experience in clinical trials in cellular therapy

Employer details

Employer name

Imperial College Healthcare NHS Trust

Address

John Goldman Centre for Cellular Therapy at Hammersmith Hospital

London

W12 0HS

Any attachments will be accessible after you click to apply.

290-SGB-138