An exciting opportunity has arisen for a Healthcare Scientist (Biomedical or Clinical) to join a busy and progressive accredited laboratory. The Cambridge Cellular Therapy Laboratory (CCTL) is a regional lab delivering cellular therapies, including providing analysis, processing, cryopreservation and storage of cells for therapeutic use. It is based on the Cambridge Biomedical Campus, the largest biomedical research campus in Europe home to two NHS flagship trusts, multiple world-class research institutes, the University Medical School and a thriving biopharma ecosystem. The lab will expand to a new purpose built facility within the Jeffrey Cheah Biomedical Centre providing 4 state of the art cleanrooms and capability to manage Class 1 and Class 2 GMOs. CCTL is becoming increasingly involved in Immune Effector Cell / AT(I)MP cell handling, and facilitates the provision of CAR-T cells for a range of indications.

Main duties of the job

You will assist with the routine stem cell transplantation and novel products service under the supervision of Senior Healthcare Scientists and the Production Manager. You will supervise and provide training to new and more junior staff members, as well as assist with validation and generation of laboratory related documents. You will be required to work on human blood and tissues in a GMP clean room environment and support the management of the Liquid Nitrogen facility.

HCPC registration is essential for this role, as is knowledge of compliance with regulatory bodies relating to tissue or cells for human use (HTA, MHRA, JACIE). Experience of working within a Quality Management System is desirable as you will provide support for the reporting, investigation and CAPA execution of Quality Events. A background in Cell Therapy, Haematology with Transfusion, Immunology or Histocompatibility and Immunogenetics would be essential. Theoretical and practical knowledge of all aspects of stem cell processing would be desirable.

About us

Our Trust

Cambridge University Hospitals (CUH) NHS Foundation Trust comprises Addenbrooke's Hospital and the Rosie Hospital in Cambridge. With over 13,000 staff and over 1100 beds the priorities of the Trust focus on a quality service which is all about people - patients, staff and partners. Recognised as providing 'outstanding' care to our patients and rated 'Good' overall by the Care Quality Commissioner, is testament to the skill and dedication of the people who work here. CUH's values - Together - Safe, Kind, Excellent - are at the heart of patient care, defining the way all staff work and behave. The Trust provides accessible high-quality healthcare for the local people of Cambridge, together with specialist services, dealing with rare or complex conditions for a regional, national and international population.

CUH is committed to promoting a diverse and inclusive community - a place where we can all be ourselves. We value our differences and fully advocate and support an inclusive working environment where every individual can fulfil their potential. We want to ensure our people are truly representative of all the communities that we serve. We welcome applications for all positions in the organisation irrespective of people's age, disability, ethnicity, race, nationality, gender identity, sex, sexual orientation, religion or belief, marriage and civil partnership status, or pregnancy and maternity status or social economic background

Job description

Job responsibilities

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities.

If you require sponsorship for a Visa to work in the UK, to avoid disappointment, please check you are not applying from a Red list country - Code of practice for the international recruitment of health and social care personnel in England - GOV.UK (www.gov.uk)

Closing date is midnight on 5th August 2024

Interviews are due to be held on 20th August 2024

Benefits to you

We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel.

Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases alternative working hours will be considered.

We welcome applications from the Armed Forces.

Person Specification

Qualifications

Essential

• Relevant BSc or equivalent
• Relevant HCPC registration, or awaiting registration with a completed certificate of competence
• IBMS specialist portfolio, equivalent post registration specialist qualification or experience

Desirable

• Relevant MSc/ PhD or equivalent
• Good Clinical Practice qualification
• Aseptic processing qualification

Experience

Essential

• Experience in a laboratory such as cell or gene therapy, haematology or blood transfusion, immunology or H& I
• Experience of completing audits
• Use of the laboratory information systems

Desirable

• Experience of working in an HTA/MHRA/JACIE licensed laboratory
• Working at GMP level
• Working in a Clean Room environment or aseptic technique
• Use of Ultra Low Temperature storage
• Leadership and supervisory experience
• Experience of out of hours working

Knowledge

Essential

• Awareness of Quality Regulations in relation to processing of cells and tissue for human application (HTA/MHRA/JACIE)
• Fully Computer literate
• Health and safety procedures, Risk Assessment and COSHH
• Awareness of Good Laboratory Practice (GLP)

Desirable

• Receipt, processing, cryopreservation and issue of cell products
• Q Pulse Quality Management System
• Haemopoietic transplants
• Immunology and Microbiology
• Cell and Gene therapy
• CAR T cell therapy

Skills

Essential

• Good verbal and written communication skills
• Able to supervise and organise junior staff
• Able to work both in a team and as an individual
• Ability to work in an organised manner, to high standards and with a very high level of accuracy and precision
• Good time management
• Self-motivated
• Ability to multi-task
• Manual dexterity
• Ability to concentrate for long periods
• The ability to problem solve and troubleshoot

Desirable

• Ability to cope under pressure
• Presentation skills
• Haemopoietic cell morphology
• Reading Agar Plates

Additional Requirements

Essential

• Flexible in relation to working times
• On-call requirement. Required to participate in the 'On-Call' rota. Travel time to hospital laboratory, less than 30 minutes, for out of hours (on-call) work
• Participate in Saturday working if needed
• The ability to understand and behave at all times, towards patients, visitors and colleagues according to the Trust values of safe, kind, excellent

Employer details

Employer name

Cambridge University Hospital NHS Foundation Trust

Address

Addenbrooke's Hospital-Division B

Hills Road

Cambridge

CB2 0QQ

Any attachments will be accessible after you click to apply.

180-B-244210