We have an exciting opportunity that has arisen at the Antimicrobial Reference Laboratory based at North Bristol NHS Trust. Band 5 analyst to join a research and bioanalysis unit working on the development of new LCMS methods to test for various antibiotics in clinical samples as part of the department research portfolio.

We are looking for an individual who is eager to learn and keen to deliver in antimicrobial research. The post holder will work closely with the senior LCMS Bioanalyst and the head of the department to undertake, in collaboration with our industrial partners, the development and validation of LCMS assays and is expected to have some experience of day-to-day running of various LCMS systems.

The assays will be undertaken to the relevant standards (UKAS / MHRA) and the post holder will assist with preparing relevant documents and reports.

Please note: this is a two year fixed term position and will terminate when the grant ends or no further funding can be obtained.

Secondments from within the NHS will be considered.

Please see the job description and person specification for further information

Please see this short video showcasing Pathology at NBT.

https://youtu.be/cJiNgR-TwUY?si=H6kkwCD5FvSv6UpW

Main duties of the job

To conduct day-to-day analysis of research / trial samples to complete the projects within the designated timeframes.

Assist the Senior Bioanalytical Analyst with validation and use of LC-MS/MS assays in research support and regulatory work.

Ensure all work is conducted in compliance with the necessary laboratory standards and regulatory requirements with the assistance of local quality assurance (QA)

Please see the job description and person specification for further information

About us

The successful candidate would be working in a team of friendly, knowledgeable & experienced analytical scientists. They will be supported by the seniors within the section as well the head of the department as we have an open door policy which means the successful candidate can request a meeting with any of the managers at short notice.

North Bristol NHS trust is the largest healthcare provider in the south west of England, and this post is located in the Pathology sciences building which has a total capacity of over 500 staff members. There are various shops on site as well as a staff canteen and coffee shop. There are multiple meeting and seminar rooms available as well as staff library located approx. 2 min walk from the department.

Please visit North Bristol NHS trust website for more comprehensive information.

Job description

Job responsibilities

To participate in the provision of effective and high-quality analytical research for sections situated within the microbiology research department.To take responsibility for the day-to-day running of samples using HPLC and LC-MS/MS techniques, also to include the maintenance, operation, and management of these equipment.Under the direction of senior analysts and managers, assist in the LC-MS/MS analysis of Phase I and II clinical trials as part of the EU research programme.Ensure all work is conducted in compliance with the necessary regulatory standards including UKAS(for clinical samples) and GCLP (for clinical trials) also liaising with and supporting the Quality Officerin Quality related issues.Organisation Chart/Accountability

Please refer to the job description and person specification for further information.

Person Specification

Education/Training/Qualifications

Essential

• A relevant BSc in science or NVQ L3 equivalent
• Evidence of Continuing Professional Development (CPD)

Work Experience

Essential

• Minimum of 5 years practical and appropriate theoretical knowledge of analytical techniques including liquid chromatography and mass spectrometry
• Minimum of 5 years practical experience in clinical or analytical laboratory

Desirable

• Knowledge of extraction techniques used on biological matrices
• Knowledge of Health and Safety legislation applicable to laboratories
• Experience of working to regulatory or accreditation standards

Knowledge/Skills/Abilities

Essential

• To be proficient in and perform laboratory techniques and analysis
• To be competent in using Laboratory LIMS and other IT systems used within the Department
• Good interpretative skills
• Able to maintain and demonstrate a thorough level of practical competence and willingness to undertake further training as required
• Good organisational skills
• Good interpersonal skills

Desirable

• Knowledge of Good Clinical Practice for Laboratories, the Medicines for Human Use (Clinical Trials) Regulations

Personal Qualities/Special Circumstances

Essential

• Good communication skills, both written and verbal
• Able to show initiative

Employer details

Employer name

North Bristol NHS Trust

Address

North Bristol NHS Trust

Bristol

BS10 5NB

Any attachments will be accessible after you click to apply.

339-SRD4785