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Senior Clinical Research Nurse

Employer
The Christie NHS FT
Location
Manchester
Salary
£43,742 to £50,056 per annum
Closing date
15 Jun 2024

View more

Profession
Nurse
Grade
Band 7
Contract Type
Permanent
Hours
Full Time
This is an exciting opportunity for a highly motivated researchnurse to join the Advanced Immune and Cell Therapy (AICT) Research Team. The AICT team is an early phase clinical trials team specialising in the delivery of cell therapy studies and complex immunotherapy trials across a range of solid cancer types. The team strives to deliver the next generation of innovative cancer treatments for solid tumors.

Examples of our cell therapy studies include CAR-T, TIL and TCR trials

The band 7 Clinical Research Nurse is expected to provide leadership of the AICT Research team, and manage a varied and growing portfolio of early phase oncology studies.

Central to this role is the responsibility of assessing and managing the care pathways including the delivery of all specified treatments for participants in research within a multidisciplinary team. Key responsibilities of the post include the co-ordination of the cell therapy and complex immunotherapy trial protocols and providing support for early phase solid tumour trial patients.

The Band 7 CRN will use their role to enhance the team's ability and capacity to undertake high quality clinical research by developing knowledge, skills, and practice within the team.

A background in research and oncology, flexibility in working, excellent communication and interpersonal skills are essential.

An informal discussion about the post is strongly recommended with the possibility to spend some time with the team.

Main duties of the job

The Band 7 CRN will be involved in every stage of the portfolio activities including feasibility reviews of new clinical trial opportunities, set-up and activation of new trials, patient recruitment and management, supporting team with data query resolution, reviewing protocol amendments, providing patient-centred insights to the research delivery team by supporting both the patients and the team through all aspects of clinical research of the AICT portfolio.

With support from the team the Band 7 CRN will ensure that the safety and wellbeing of the patients is maintained within the requirement of the multi-regulatory frameworks for clinical research ensuring compliance with ICH/GCP standards and Trust SOPs.

They will provide support, induction, continued supervision and management of the AICT research team.

By utilising national frameworks for auditing patients experience the Band 7 CRN will ensure the patients participating in AICT portfolio studies will have the best possible experience whilst participating in clinical research.

They will raise the profile of the clinical research nurse and clinical trials within the trust by engaging in promotional events relating to clinical research with attendance and contributions at local, national and international meetings.

Demonstrate awareness and contribution to divisional, Trust and national objectives and strategies.

About us

The Christie is one of Europe's leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world chemotherapy on site and through 14 other hospitals highly specialist surgery for complex and rare cancer and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

Job description

Job responsibilities

DUTIES AND RESPONSIBILITIES

Clinical Research Co-ordination

Work autonomously in all areas of practice relating to clinical research.

Understand and deliver care in accordance with regulatory approved clinical research protocols.

Oversee the process for obtaining NHS permissions (R& D approval) for clinical trials within team. As project lead, ensures permissions are in place prior to any patient recruitment.

Undertake feasibility and risk assessments of clinical trial protocols in conjunction with Team Leader, Principal Investigator and Senior Clinical Trials Co-Ordinator

Ensure all clinical trial activities are recorded in appropriate systems in a timely manner.

Awareness of trial specific, regional, and national targets.

Initiate new recruitment strategies for recruiting patients to clinical trials including engagement with the research network.

In conjunction with Team Leader lead on the delegation of all trial related activities to research team members (clinical and administrative) and ensure compliance with SOPs and ICH/GCP.

Work with team leader and sponsor companies in the preparation and negotiation of financial contracts for individual trials.

Arrange and facilitate clinical trial related meetings.

In conjunction with Team Leader, oversee appropriate financial remunerations for clinical trial activity

Clinical Service and Professional Responsibilities

Assimilation of highly complex information relating to clinical trials and communication to patients at a level appropriate to their understanding. Ensure highly sensitive information is communicated to patients, relatives, and careers regarding prognosis

Responsible for the development, implementation, and review of specialist care pathways in conjunction with appropriate personnel.

Demonstration of expert knowledge in specialist area to maintain clinical excellence.

Set up processes/patient pathways in conjunction with appropriate personnel from specialist research areas to promote a cost-effective timely service for individual protocols (shared care pathways, specialist clinics, etc.).

Support Team Leader in delivering divisional and trust strategic objectives including performance indicators and metrics.

Escalation of governance issues impacting on delivery of job purpose.

To act as a primary contact point for the clinical trial patients and act as adviser to other health care professionals.

Responsibility for maintenance and development of professional knowledge and practice by attending mandatory and specialist training (e.g., GCP) in accordance with local policy

Ensuring care delivery standards in accordance with trial protocol, local policy, NMC Code of Practice Conduct and current best practice

Development and maintenance of a high-quality service by:

o Overseeing the safe administration of all licensed and unlicensed medicinal products within the context of a clinical trial.

o Overseeing assessment and evaluation of treatment toxicities and initiation of appropriate intervention.

o Contribute to development of specialist Standard Operating Procedures and guidelines

Provide education and support for non-research staff in the delivery of protocol driven treatment for all patients.

Participate in monitoring and audit activities within research team

To carry out non-medical prescribing within scope of professional practice and in accordance with local policies and procedures and national legislation (optional and depending on clinical service needs).

Personal Education, Training and Development

Maintain professional development whilst evaluating own specialist knowledge and practice through a process of appraisal and personal development planning.

Promote the role of the clinical research nurse as an integral part of the healthcare system.

Increase and maintain awareness of current advances in cancer treatments, research and nursing practice thereby maintaining the highest standard of care for patients with cancer and implementing evidence-based care by continuing professional development.

Participation in trust-wide education programs and study days.

Obtain clinical supervision as appropriate.

To keep up to date with departmental, Trust, UK and EU developments for the management of clinical research ensuring timely, effective implementation of changes.

Attendance at team and divisional meetings.

Staff Management and Development

In conjunction with the team leader, provide the induction, continued supervision and management of the research teams.

In conjunction with the team leader, be responsible for ensuring all members of the research nurse team undergo regular appraisal and support appropriate training and development opportunities in line with role requirements.

Lead on the development of specialist study days within own research team

Provide specialist education and training in relation to clinical trials to all key stakeholders.

Disseminate information by attendance and /or presentations at local, national and international conferences/meetings

Be responsible for the development of members of the research team.

EU DIRECTIVE ICH/GCP

All personnel involved in clinical research have a responsibility to ensure that clinical trials are conducted in accordance with the EU Directive and ICH/GCP.

Person Specification

Qualifications

Essential

  • Registered General Nurse - Currently registered with the Nursing & Midwifery Council
  • First Degree or relevant experience
  • GCP/ICH recognised recent training


Desirable

  • Post-graduate qualification in oncology and/or clinical research


Experience

Essential

  • Relevant oncology nursing experience.
  • Clinical research experience at Band 6 or other relevant experience related to specialism
  • Experience in coordinating clinical trials from initiation to closure including archiving
  • Proven evidence of service improvement
  • Experience of working autonomously and part of a multi-disciplinary team
  • Ability to organise and prioritise own workload


Desirable

  • Experience of managing Clinical Research Teams
  • Experience of clinical audits both internal and external
  • Experience of writing standards operating procedures for clinical research and individual protocols


Skills

Essential

  • Highly effective communication skills
  • Effective team working across professional and organisational boundaries
  • Good written and analytical skills
  • Involvement in informed consent process within scope of professional practice
  • Co-ordinates care pathway for patients and carers participating in clinical research
  • Manages, assesses and supports the physical and psychological needs of the patient and carer
  • Able to manage work autonomously
  • Training and leadership skills
  • Demonstrable IT Skills able to use Word, PowerPoint, Excel and Outlook


Desirable

  • Intra-venous access and cannulation skills administration of clinical trial therapies
  • Good presentation skills


Knowledge

Essential

  • Has a working and intellectual knowledge of the purpose of clinical research
  • Has specialist knowledge of Research Ethics Committees and has been actively involved in the process of gaining relevant clinical trial approval and is able to guide members of the research team through the approval process
  • Knowledge of professional and NHS issues and policy relating to specialist area
  • Maintain Professional development and have an awareness of current nursing issues


Desirable

  • Knowledge of Research Ethics Committees.
  • Knowledge of the purpose of clinical research


VALUES

Essential

  • Ability to demonstrate the organisational values and behaviours


OTHER

Essential

  • Maintain professional development and have an awareness of current nursing issues
  • Demonstrates flexibility in working hours


Desirable

  • Assertiveness


Employer details

Employer name

The Christie NHS FT

Address

Business Planning - Q01523

Wilmslow Road

Manchester

M20 4BX

Any attachments will be accessible after you click to apply.

413-82845-RI-SD

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