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Clinical Research Nurse

The Christie NHS FT
£35,392 to £42,618 pro rota, per annum
Closing date
11 Jun 2024

View more

Band 6
Contract Type
Full Time
We are looking for a highly motivated nurse, interested in helping to improve patient treatment outcomes for patients affected by Haematological malignancies.

Research nursing is an exciting and developing role, supported through the R& I division with a good education and development package in place to ensure that staff reach their potential.

This post presents an excellent opportunity to join the Haematology Research team, manage a varied portfolio of oncology studies, from early to later phase clinical trials.

Central to this role is the responsibility of assessing and managing the care pathways including the delivery of all specified treatments for participants in research within a multidisciplinary team. Key responsibilities of the post include the co-ordination of the trial protocols and support for haematology patients.

A background in oncology, flexibility in working, excellent communication and interpersonal skills are essential. Experience in clinical research and/or haematological malignancies would be desirable.

An informal discussion about the post is strongly recommended with the possibility to spend some time with the team to understand better the requirement of the role.

Main duties of the job

The CRN will be involved in every stage of the portfolio activities including feasibility reviews of new clinical trial opportunities, set-up and activation of new trials, patient recruitment and management, supporting team with data query resolution, reviewing protocol amendments, providing patient-centred insights to the research delivery team by supporting both the patients and the team through all aspects of clinical research of the Haematology portfolio.

With support from the team the CRN will ensure that the safety and wellbeing of the patients is maintained within the requirement of the multi-regulatory frameworks for clinical research ensuring compliance with ICH/GCP standards and Trust SOPs.

You will work collaboratively with the other members of the study team and with the wider multi-disciplinary research community. You will have excellent communication and interpersonal skills, possess strong motivation and have the ability to work independently.

By utilising national frameworks for auditing patients experience the CRN will ensure the patients in the Haematology disease portfolio studies will have the best possible experience whilst participating in clinical research.

Raise the profile of the clinical research nurse and clinical trials within the trust by engaging in promotional events relating to clinical research with attendance and contributions at local, national and international meetings.

About us

The Christie is one of Europe's leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world chemotherapy on site and through 14 other hospitals highly specialist surgery for complex and rare cancer and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

Job description

Job responsibilities


Clinical Research Co-ordination
  • Work autonomously in all areas of practice relating to clinical research.
  • Understand and deliver care in accordance with regulatory approved clinical research protocols.
  • Understand the process for obtaining NHS permissions (R& D approval) for conducting clinical trials at site. As project lead, ensure permissions are in place prior to any patient recruitment.
  • Participate in clinical trial feasibilities and risk assessments of clinical trial protocols.
  • Ensure all clinical trial activities are recorded in appropriate systems in a timely manner.
  • Awareness of trial specific, regional and national targets. Identify and implement strategies for recruiting patients to clinical trials ensuring that targets for patient recruitment are delivered.
  • Delegation and oversight of research related activities to research team members (clinical and administrative) and ensure compliance with SOPs and ICH/GCP.
  • Arrange and facilitate clinical trial related meetings.
  • Involvement in appropriate financial remunerations for clinical trial activity.

Clinical Service and Professional Responsibilities
  • Assimilation of highly complex information relating to clinical trials and communication to patients at a level appropriate to their understanding. Ensure highly sensitive information is communicated to patients, relatives and carers regarding prognosis
  • Contribute to the development, implementation and review of specialist care pathways in conjunction with appropriate personnel.
  • Demonstration of expert knowledge in specialist area to maintain clinical excellence.
  • Demonstrate awareness of divisional and trust strategic objectives including performance indicators and metrics.
  • Escalation of governance issues impacting on delivery of job purpose.
  • To act as a primary contact point for the clinical trial patients and act as adviser to other health care professionals.
  • Responsibility for maintenance and development of professional knowledge and practice by attending mandatory and specialist training in accordance with local policy.
  • Ensuring care delivery standards in accordance with trial protocol, local policy, NMC Code of Practice Conduct and current best practice.
  • Development and maintenance of a high quality service by:
  • Overseeing the safe administration of all licensed and unlicensed medicinal products within the context of a clinical trials
  • Overseeing assessment and evaluation of treatment toxicities and initiation of appropriate intervention.
  • Contribute to development of specialist Standard Operating Procedures and guidelines.
  • Provide education and support for non-research staff in the delivery of protocol driven treatment for all patients.
  • Participate in monitoring and audit activities within research team
  • To carry out non-medical prescribing within scope of professional practice and in accordance with local policies and procedures and national legislation (optional and depending on clinical service needs).

Personal Education, Training and Development
  • Maintain professional development whilst evaluating own specialist knowledge and practice through a process of appraisal and personal development planning.
  • Promote the role of the clinical research nurse as an integral part of the healthcare system.
  • Increase and maintain awareness of current advances in cancer treatments, research and nursing practice thereby maintaining the highest standard of care for patients with cancer and implementing evidence based care by continuing professional development.
  • Participation in trust-wide education programmes and study days.
  • Obtain clinical supervision as appropriate.
  • To keep up to date with departmental, Trust, UK and EU developments for the management of clinical research ensuring timely, effective implementation of changes.
  • Attendance at team and divisional meeting Staff Management and Development
  • To Support the Senior Clinical Research Nurse in the induction and continued supervision of junior members of staff, ensuring compliance with regulatory compliance and legislation.
  • Support the development of specialist study days within own research team.
  • Assist in the provision of specialist education and training in relation to clinical trials to all key stakeholders.
  • Disseminate information by attendance and /or presentations at local, national and international conferences/meetings
  • Contribute to the development of members of the research team

EU DIRECTIVE ICH/GCP All personnel involved in clinical research have a responsibility to ensure that clinical trials are conducted in accordance with the EU Directive and ICH/GCP.

Person Specification



  • Registered General Nurse - Currently registered with the Nursing & Midwifery Council.
  • First Degree or relevant clinical experience


  • Post-graduate qualification in oncology and/or clinical research GCP/ICH recognised recent training



  • Experience of oncology nursing.
  • Experience of working autonomously and as part of a Multi-disciplinary team.
  • Ability to demonstrate evidence of service improvement


  • Experience of working in a clinical research environment.



  • Highly effective communication skills Advance organisational skills
  • Good written and analytical skills
  • Able to manage work autonomously and manage own workload
  • Demonstrable IT Skills - able to use Word, PowerPoint, Excel and Outlook


  • Intra-venous access and cannulation skills administration of IV chemotherapy
  • Good presentation skills



  • Knowledge of the clinical trial process Knowledge of ICH-GCP
  • Knowledge of research governance framework
  • Knowledge of professional and NHS issues and policy relating to specialist area


  • Knowledge of Research Ethics Committees
  • Knowledge of the purpose of clinical research.



  • Ability to demonstrate the organisational values and behaviours



  • Maintain professional development and have an awareness of current nursing issues.
  • Demonstrates flexibility in working hours


  • Assertiveness

Employer details

Employer name

The Christie NHS FT


Haematology - Q00675


M20 4BX

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