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Clinical Research Fellow - Trust Doctor in Medicine

University College London Hospitals NHS Foundation Trust
£34,769 to £39,152 Per annum plus London Weighting
Closing date
24 May 2024

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The post holder will be required to work as a Clinical Research Fellow taking responsibility for the coordination and support of the UCLH-Crick Legacy study and other relevant clinical trials in COVID-19 such as STIMULATE-ICP. The Legacy study is a multicentre consortium built from Clinicians and Group Leaders from across the Francis Crick Institute and University College London Hospitals that tackles issues at the front-line of the on-going pandemic. Key aims include the study of coronavirus infection to develop understanding of the dynamics of pandemics such as Covid-19.

Legacy utilises a unique bank of clinical samples gathered as part of the Crick Institute's COVID-19 testing facility providing a remarkable resource for the investigation of facets of COVID-19 including immunity against emerging SARS-CoV-2 Variants of Concern (Wall et al., Lancet, 2021a Wall et al., Lancet, 2021b), disease progression (Townsley et al., medRxiv, 2022), the impact of prior infection on immunity (Wu et al., Lancet, 2022a) vaccine efficacy and vulnerability of populations such as healthcare workers that can be used to inform policy on health and safety.

Main duties of the job

Legacy also directly interfaces with other UCLH COVID studies examining the effect of the pandemic on different patient groups, including the NIHR funded STIMULATE-ICP trial. STIMULATE-ICP a large multi-centre trial investigating the symptoms, trajectory & pathogenesis of Long COVID in patients with persistent symptoms > 12 weeks after primary COVID-19 infection. The causes of Long COVID remain unknown, & over 2 million people in the UK are estimated to be affected over the last 3 years. The post holder will undertake clinical work in the Post-COVID clinic at UCLH, & work on a reverse translational sub-study within the trial at the Francis Crick Institute, to test hypotheses on the causes of Long COVID & examining the immunological phenotypes underpinning a range of COVID-19 symptoms.

The primary role of the post holder is to undertake medical duties in line with the highest safety standards for trial participants & in compliance with Ethical & Good Clinical Practice principles & regulatory standards. The post holder will be delivering day-to-day research - i.e. following the protocol, assessing suitability & obtaining consent for research, undertaking full medical assessments of clinical trial participants including full physical & neurological examinations, ECG interpretation, laboratory test interpretation.

About us

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.

We provide first-class acute and specialist services across eight sites:
  • University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
  • National Hospital for Neurology and Neurosurgery
  • Royal National ENT and Eastman Dental Hospitals
  • University College Hospital Grafton Way Building
  • Royal London Hospital for Integrated Medicine
  • University College Hospital Macmillan Cancer Centre
  • The Hospital for Tropical Diseases
  • University College Hospital at Westmoreland Street

We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.

We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.

Job description

Job responsibilities

Responding to safety concerns regarding trial participants is a key function of this role so experience regarding the acute assessment of the unwell patient & ALS certification is essential.

Whilst the post is not formally approved for physician training from Core Medical Training (CMT) or Specialty Training (ST), it provides an ideal opportunity for gaining experience in clinical trials & we would welcome applicants with a broad range of general medical experience including GIM, Infectious Diseases, General Practice & Emergency Medicine. The post holder will have access to the resources & opportunities that are available to specialist trainees in the departments of Clinical Virology, Microbiology & Infectious Diseases & will collaborate with clinical teams, other fellows, nurses, other clinical staff & laboratory biomedical scientists.

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

Come and be a part of the best NHS trust in England to work for, according to our staff*

UCLH top trust to work at in England for the second year running! : University College London Hospitals NHS Foundation Trust

*In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England for the second year in a row.

UCLH top trust to work at in England for the second year running! : University College London Hospitals NHS Foundation Trust.

Once again, UCLH has received the highest score of all general acute and acute/community NHS trusts in England for staff that would recommend us as a place to work.

Person Specification

Knowledge and Qualifications


  • Medical qualification MBBS with full valid registration at GMC
  • Valid ALS training certification


  • GCP trained by start date



  • Minimum of 2 years post registration experience
  • Familiarity with principle of clinical research including Good Clinical Practice.
  • Experience of phlebotomy and cannulation
  • NHS clinical experience (at FY2 or equivalent level) and named Responsible Officer


  • Experience of receiving consent
  • Experience in the conduct of clinical trials
  • Experience of formal/ informal teaching of patients and staff

Skills & Abilities


  • Ability to learn and implement new study related clinical skills
  • Excellent interpersonal, verbal and written communication skills able to speak English to level required to fulfil job requirements
  • Demonstrates evidence of professional development
  • Demonstrates academic achievement appropriate to level of appointment
  • Computer literacy

Personal Qualities


  • Demonstrates commitment and preparedness
  • Enthusiastic nature
  • Demonstrates honesty, integrity and appreciation of ethical dilemmas
  • Reliability - demonstrates punctuality, attendance and sense of responsibility

Other requirements


  • Able to work flexibly on occasion

Employer details

Employer name

University College London Hospitals NHS Foundation Trust


University College Hospital

235 Euston Road



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