Passionate about innovation in cancer treatments?

Thinking about including experience in clinical research in your career?

This post is a great opportunity to be part of a dedicated pharmacy clinical trials team delivering a high quality and responsive service to patients, clinical staff and sponsors who use our services in adult cancer research.

Main duties of the job

In addition to the below summary you need to familiarise yourself with full job description and person specification documents attached to this advert.

You will be the pharmacy lead for commercial trials in adult cancer, responsible for appraisal of all relevant clinical trials including costing and all aspects of pharmaceutical input in accordance with legal requirements and Good Clinical Practice relating to the prescribing, handling, dispensing, administration, storage and disposal of investigational medicinal products (IMPs) and non investigational medicinal products (NIMPs).

You will advise and work with the chemotherapy production unit team with regard to issues relating to Good Manufacturing Practice and commercial trials in adult cancer and contribute to the delivery of a high quality specialist clinical pharmacy service to adult cancer.

You will be based on the City Campus with some cross-town working as required to meet the demands of the pharmacy cancer trials service.

You will be responsible for individual portfolio of cancer clinical trials, with the expectation of close working and cross-cover, as required with your specialist cancer clinical trials pharmacists colleagues.

About us

NUH is an acute care, research active teaching hospital who in partnership with Nottingham University hosts a Biomedical Research Centre and Clinical Research Facility conducting research into hearing, digestive, respiratory and musculoskeletal disease, mental health and imaging.

NUH recognises the vital role pharmacy has in the management of robust clinical research and NUH Research and Innovation department supports a number of our posts to ensure we can deliver a safe, efficient and responsive clinical trials service.

You will have a close working relationship with all members of the pharmacy trials team of pharmacists, technicians and assistants and have regular contact with clinical research staff and Pharmaceutical companies

NUH has a nationally-recognised staff wellbeing programme and as recently voted as one of the Sunday Times Best Places to live, our city and the region are one of the big reasons why a career at NUH is the right choice for so many. The city has been named in the top ten places to bring up a family and the top UK city to make your salary stretch further.

For further information or an informal chat please contact the current post holder Chris Pudney by phone on 01159691169 ext 79414 or christopher.pudney@nuh.nhs.uk

Job description

Job responsibilities

JOB SUMMARY

To be the pharmacy lead for commercial trials in adult cancer.

To be responsible for appraisal of all relevant clinical trials including costing and all aspects of pharmaceutical input in accordance with legal requirements and Good Clinical Practice relating to the prescribing, handling, dispensing, administration, storage and disposal of investigational medicinal products and non investigational medicinal products

To advise and work with the chemotherapy production unit team with regard to issues relating to Good Manufacturing Practice and commercial trials in adult cancer.

To contribute to the delivery of a high quality specialist clinical pharmacy service to adult cancer.

The post holders will be based at City Campus

The post holder will be responsible for individual portfolio of cancer clinical trials with an expectation of close working and cross-cover, as required with other specialist cancer clinical trials pharmacists

KEY JOB RESPONSIBILITIES

Service Management and Development

Attends specialty clinical trials meetings.

Together with the Research teams, Senior Cancer Services Pharmacist and the Principal Pharmacist Research and Innovative Treatments, identifies and prioritises clinical trial pharmacy services to commercial adult cancer to ensure national and local agendas are delivered.

Develops, implements and audits pharmacy clinical trials practices with regards to commercial adult cancer

Liaises with Cancer trials pharmacists across the East Midlands Cancer Network and wider where appropriate, to share working and work towards equity of care with regards to cancer clinical trials across the network.

Provides expert advice regarding commercial adult cancer trials to the Pharmacy Department, relevant specialties, consultant teams, research teams and other clinical specialities.

Supports the maintenance and use of the chemotherapy e-prescribing system in commercial adult cancer trials, to include set-up and validation of new medicines, chemotherapy and trials regimens, and up-date of existing medicines and regimens.

Supports the Chief Pharmacist and the Principal Pharmacist, Research and Innovative Treatments in specific cancer clinical trials management issues and projects.

Participates and supports the development of business plans and department and clinical strategies, e.g. in response to expansion of services, new consultant appointments, national initiatives and locally identified risks.

Contributes to the overall organisation, administration and management of the Pharmacy Clinical trials and Cancer Services teams.

Clinical Trials Service (80%)

Takes responsibility for the provision, management and development of a high quality, comprehensive specialist clinical trials pharmacy service to commercial adult cancer

Works according to Good Clinical Practice guidelines and agreed pharmacy clinical trials procedures.

Critically appraises commercial adult cancer clinical trials protocols, including amendments, to assess feasibility and ensure all pharmaceutical aspects of the study are deliverable and safe, in liaison with the pharmacy production unit staff as required.

Calculates pharmacy support costs for commercial adult cancer clinical trials protocols, liaising with the speciality research teams, sponsors and NUH Research and Innovation Department.

Liaises with NUH R& I and research teams, to ensure timely appraisal, costing and pharmacy approval for clinical trials in commercial adult cancer

Leads and finalises the set-up of clinical trials in commercial adult cancer i.e. writing and/or checking dispensing procedure, and manufacturing worksheets where applicable.

Is accountable for adherence to protocol requirements for investigational medicinal product (IMP) management

Participates in the provision of a clinical pharmacy service for patients recruited into clinical trials within the Trust

Assesses and clinically verifies trial specific prescriptions to ensure safe and rational prescribing according to the study protocol

Provides trial medication and any supporting treatment for inpatient, discharge or outpatient use.

Counsels patients to ensure medication usage according to the protocol and to improve patient understanding of medication using trial specific patient information.

Assesses patient compliance via review of trial medication returned by trial subjects and patient counselling

Contributes to detection of possible adverse events and prompt notification of the investigator and sponsor, where relevant

Accuracy checks prescriptions, dispensed by others, for accuracy of interpretation, supply, labelling and accountability recording.

Clinical Practice (20%)

Supports the provision, of a high quality, comprehensive specialist pharmacy service

Demonstrates professional accountability to patients under their care.

Provides specialist advice and guidance on all issues relating to prescribing and therapeutics of drugs in line with national and local guidelines.

Uses specialist knowledge and experience, and appraises information from numerous sources to provide highly specialised advice on drug therapy to medical, nursing and pharmacy staff. This may include advice about experimental medicines or of medicine use where limited evidence exists.

Assesses and verifies prescription and charts and prescribing, including chemotherapy, in order to ensure safe, rational and effective prescribing within existing guidelines.

Identifies potential adverse reactions to medicines, drug interactions and Intravenous drug compatibility issues.

Establishes drug histories and enables the use of patients own medicines.

Counsels patients on their drug therapy to improve medication usage and patient understanding of their medication during in-patient stay and after discharge.

Provides medications for individual patients during their stay in hospital and at discharge as necessary.

Requests and interprets clinical tests and serum drug levels to monitor and make recommendations to improve effectiveness of drug therapy.

Pro-actively liaises with other members of the multidisciplinary team in order to make recommendations about drug therapy to improve patient outcomes.

Encourages and monitors adherence to hospital formulary, trial protocols and national guidelines.

Amends prescriptions on verbal orders from prescribers and transcribes prescriptions for patients being discharged.

Is accountable on the clinical areas served for adherence to all pharmacy policies and procedures relating to medicines management.

Works with the other pharmacists in the provision of a high quality clinical pharmacy service to wards in the hospital as directed by the Assistant Head of Pharmacy - Clinical Services Lead

Provides professional supervision in the dispensary by:

Checking and release of manufactured/dispensed medicines, in accordance with good manufacturing practice and departmental procedures.

Accurately interpreting and clinically screening prescriptions, referring to relevant protocols and intervening when necessary.

Financial Resource Management

Calculates the cost of pharmacy support for clinical trials protocols in commercial adult cancer liaising with the specialty research teams, sponsors and NUH R& I Department.

Identifies potential cost savings and/or efficiency initiatives in medicines usage, relevant to clinical trials.

Ensures trials fees are invoiced and reclaim mechanisms for the medicine costs are accounted for and implemented, liaising with the Specialist Pharmacist High-cost drugs management.

Produces reports regarding cost-savings / costs-avoided via recruitment of patients into commercial cancer clinical trials at NUH, to inform the specialties and satisfy agreements with commissioners.

Human Resource Management

Acts as a role model

Supervises and teaches junior staff

Leads on the submission of business cases to secure funding for service developments/new pharmacy posts within the specialty.

Assists in the recruitment of new staff

Contributes to the performance and line management of pharmacy staff working within the Clinical trials teams, including appraisals.

Research and Development

Undertakes, supervises and participates in research, and if suitable registers for a further degree (e.g. DPharm, MPhil).

Actively evaluates and integrates research evidence into practice to develop and improve pharmacy services within the directorate and the department.

Maintains contact with appropriate national and local specialist groups to facilitate best practice to be identified and incorporated into NUH practice.

Education and Training

Works with the Principal Pharmacist, Research and Innovative Treatments, and the Education & Training pharmacists to provide and develop a competency framework, training plans and materials on issues relating to Clinical Trials to ensure training facilities for Advanced Specialist Pharmacy Practice Framework are available

Delivers teaching to nursing, medical, pharmacy and other AHP staff about medication issues within Clinical Trials and the relevant specialties, as appropriate

Provides education, training and assessments for pharmacists on Clinical Diplomas, Pre-Registration Pharmacists, other pharmacy, nursing and medical staff.

Develops and maintains portfolio of Specialist Pharmacist Practice. Undertakes and documents Continuing Professional Development.

General

Participates in rostered flexible working including weekend and bank holiday arrangements in line with service commitments.

Participates in the back-up on-call service for shift working pharmacists as required.

Undertakes any other duties that may reasonably be required as agreed by senior staff.

Person Specification

Training and Qualifications

Essential

• BPharm/BSc or MPharm/MSc or equivalent
• Current General Pharmaceutical Council registration
• Member of the RPharmS.
• Diploma/MSc in Clinical Pharmacy, or relevant postgraduate experience
• Awareness of Good Clinical Practice (GCP)

Desirable

• Current GCP certification.

Experience

Any attachments will be accessible after you click to apply.

164-5780781