The role is to provide and develop a focus for PET-CT related research in order to improve patient outcomes from clinical imaging, direct education and teaching courses and support other research staff. The areas of interest are wide ranging and will allow considerable scope to deliver high impact work. The role requires a good physics education to PhD level and extensive post-graduate experience in analytical techniques applied to medical imaging with good communication skills to enable effective collaboration in a multi-disciplinary environment. The position is supported by a well-established infrastructure of clinical, scientific and educational staff at The Christie, research expertise in the Nuclear Physics group at The University of Manchester and development/delivery expertise in a number of commercial collaborators. There is ready access to high specification imaging and computing resources as well as anonymised clinical and phantom images including from printed 3D phantoms.Main duties of the job
This position has been established to strengthen research and innovation in Nuclear Medicine and particularly in developing quantitative imaging in PET-CT. Areas of interest also include: evaluating the imaging potential and production requirements of novel radionuclides for both imaging and theranostic applications; and evaluating the current and develop novel applications for Artificial Intelligence. The work is likely to involve: undertaking Monte Carlo modelling; defining and designing anthropomorphic 3D phantoms; and performing dose calculations using various dosimetry calculation platforms. The experience/skills required include: post graduate research experience involving MC simulation and practical experimental work; data analysis, including the use of Matlab (or similar packages); and knowledge of one or more computer programming languages (eg C++, Java, IDL). The knowledge/experience desired include: nuclear medicine physics; working with radioactivity; and 3D printing.About us
The post holder will be part of The Christie PET-CT Academy and will be based in the Nuclear Medicine group of the Medical Physics department, which comprises approximately 50 clinical scientific and imaging staff. They will work in collaboration with the Molecular Imaging Group of the Radiology department and also the Nuclear Physics group at The University of Manchester as well as the Nuclear Medicine department at the Manchester University NHS FT and industrial partners, as required. This will provide exposure to a large active research network and to a high quality clinical PET-CT service which is QSI accredited. The well-established scientific and clinical infrastructure has been proven to provide high level mentorship and encouragement for achievement/development in a supportive atmosphere. The Academy offers opportunity, in conjunction with Alliance Medical, to help further develop PET-CT imaging in an extensive collaborative network of clinical centres throughout NHS England.Job descriptionJob responsibilities
1. General Duties
1.1. Ensure all work complies with current UK legislation for work with ionizing radiation (IRR 2017, IR(ME)R 2017) and the Quality Management System for the provision of nuclear medicine.1.2. The post holder is expected to undertake an agreed scheme for Continuing Professional Development (CPD).1.3. The place of work is normally The Christie, Withington, but the post holder may be required to carry out work at the University of Manchester1.4. Hours are normally worked flexibly between 7:30 and 20:00, Monday to Friday.
2. Specific Duties
2.1. Specific duties will involve work in a number of the following areas:2.2. Actively encourage and support the culture of research and innovation in Christie Nuclear Medicine2.3. Support the work of the Christie in developing quantitative imaging in PET-CT for disease interpretation, patient diagnosis and response assessment to improve patient outcomes2.4. Evaluate the imaging potential and production requirements of novel radionuclides for PET-CT imaging and theranostic applications2.5. Evaluate current and develop novel applications for Artificial Intelligence and use of Big Data in PET-CT and SPECT/CT2.6. Undertake Monte Carlo modelling of acquisitions and dose in theranostic radionuclides2.7. Define and design quasi-realistic anthropomorphic 3D phantoms based on selected diseases and radioactivity distributions2.8. Instil radioactivity, carry out hybrid imaging and evaluate current and novel quantification techniques using quasi-realistic anthropomorphic 3D phantoms2.9. Perform dose calculations using ChristieDose and / or other dosimetry calculation platforms, for both Monte Carlo - simulated hybrid imaging data and data from quasi-realistic anthropomorphic 3D phantoms
3.1. Collaborates and liaises closely with colleagues at the University of Manchester and industrial partners.3.2. Demonstrates excellent communication skills involving highly complex issues and information.3.3. Arranges programmes for, and chairs, meetings; this also includes teaching sessions.3.4. Plans study protocols and methods.3.5. Collects and analyses data for research studies in collaboration with the project teams.3.6. Prepares scientific papers arising from the research and co-ordinates their submission to peer reviewed journals.3.7. Presents reports of research to local, national or international meetings; involving large groups.3.8. Assists with practical aspects of research studies where required.
4. Teaching and TrainingAssists with the provision of the Nuclear Medicine groups teaching and training programmes.Person SpecificationQualificationsEssential
- Ph.D. Medical Physics, Applied Physics or related field
- Post graduate research experience
- Experience with Monte Carlo simulation
- Significant practical experimental work
- Work with radioactive materials Experience with 3D printing
- Data analysis, including use of Excel, Access and Matlab (or similar packages).
- Scientific report writing/track record of publications in scientific journals and conferences.
- Good manual dexterity for using intricate equipment
- Use of computer-based dosimetry software.
- Knowledge of one or more computer programming languages (e.g. C++, Java, IDL)
- Knowledge of nuclear medicine physics
- Ability to demonstrate the organisational values and behaviours
- Occasional unsocial hours for experimental work and occasional travel to other sites and for scientific meetings
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